You can split it off and have your Python code be an API you call, but now you have at least two languages involved (Python+Elixir, plus JS somewhere, plus the

You can split it off and have your Python code be an API you call, but now you have at least two languages involved (Python+Elixir, plus JS somewhere, plus the possible mix of C/C++/Fortran/Rust(maybe?)). Given Ruby on Rails was mentioned, just using Django seems similarly like the least risky thing to do (this all assumes you are doing numerical stuff, not just a standard CRUD app).