I don't think it's necessarily infix math. Most code is not math heavy. But code bases tend to be heavily loaded with those language features that drive program

I don't think it's necessarily infix math. Most code is not math heavy. But code bases tend to be heavily loaded with those language features that drive program organization, like object-orientation. Common Lisp's "problem" isn't so much (* x (y + z)) but rather (fun (slot-value foo 'bar) (slot-value (slot-value xyzzy 'bag) 'element)). The with-slots macro is not really an answer. It's an extra blurb you have to write, for something simple that just looks like fun(foo.bar, xyzzy.bag.element) in another language. Slot readers and accessors help. If the class you're using hasn't defined them, should you? I have a suspicion that newcomers to Lisp who are able to get past the way arithmetic is written balk when they see how object oriented-glue code looks. The focus on infix may be misplaced.