I've worked like you described for years and it mostly works. Although I've recently started to experiment with a new uv based workflow that looks like this:

I've worked like you described for years and it mostly works. Although I've recently started to experiment with a new uv based workflow that looks like this: To open a notebook I run (via an alias) uv tool run jupyter lab and then in the first cell of each notebook I have !uv pip install my-dependcies This takes care of all the venv management stuff and makes sure that I always have the dependencies I need for each notebook. Only been doing this for a few weeks, but so far so good.