> I did see Veritasium's video on this, and have been generally familiar with AlphaFold, but it remains unclear to me how the safety and efficacy of the antiven

> I did see Veritasium's video on this, and have been generally familiar with AlphaFold, but it remains unclear to me how the safety and efficacy of the antivenoms' designed with its help would be ensured short of a regular clinical trial gauntlet, which I understand continues to be extremely costly and long on its own. Well that one will have to be done for any medicine, the problem is snake and spider bites are rare in the Global North countries [1], but pretty prevalent in Global South countries. That means that there isn't much money in getting antivenins through certifications, there are dozens of majorly relevant species and hundreds of lesser importance which means a ton of expenses even if the antivenins share superstructures, and we'd run into the same issue as with the Covid vaccines - the accusation of local populations that they will be used as testbeds. [1] https://en.wikipedia.org/wiki/Epidemiology_of_snakebites https://en.wikipedia.org/wiki/Epidemiology_of_snakebites