3 ms·
One thing that a lot of these kinds of articles don't mention is that tolerance effects in drugs tend to be at least somewhat dosage dependent, and there is som
by mistercow 14y ago
One thing that a lot of these kinds of articles don't mention is that tolerance effects in drugs tend to be at least somewhat dosage dependent, and there is some evidence that this is the case with caffeine[1]. Look at amphetamines, for example; at large doses they have a large tolerance effect and are highly addictive. At small doses the tolerance effect is smaller, and they are non-addictive, yet still therapeutic against disorders like ADHD.
It's reasonable, therefore, to suppose that there should be a "sweet spot" for caffeine use, where the tolerance you build is small, but the effects are still significant.
It's also worth mentioning that "tolerance" is not an all or nothing thing. With nicotine and amphetamines, there is a tolerance effect, but some of the effects of those drugs actually become stronger with regular use (and this is believed to play a role in the formation of addictions to those substances)[2]. So while tolerance and withdrawal are real problems, it is a myth that addicts merely return to the baseline in all respects when exposed to the drug they're addicted to.
In any case, if you are bothered by caffeine side effects, you might want to get some theanine. It's cheap, relatively flavorless, and when used in a 2:1 ratio with caffeine, it's been shown to reduce the side effects of caffeine[3], while adding some other cognitive benefits besides what you get from caffeine alone[3][4].
[1] http://www.sciencedirect.com/science/article/pii/0091305788901797 http://www.sciencedirect.com/science/article/pii/00913057889...
[2] http://www.ncbi.nlm.nih.gov/pubmed/14592678 http://www.ncbi.nlm.nih.gov/pubmed/14592678
[3] http://www.ncbi.nlm.nih.gov/pubmed/18006208 http://www.ncbi.nlm.nih.gov/pubmed/18006208
[4] http://www.ncbi.nlm.nih.gov/pubmed/18681988 http://www.ncbi.nlm.nih.gov/pubmed/18681988
- peregrine 14y agoI second Theanine. Personally I've been taking it before my morning coffee and I notice that I am less jittery and less stressful, while still having that caffeine high. I will even take it alone sometimes before a high stress situations and it helps with the nerves. I oftentimes choose to consume Green Tea or Matcha as they contain a varying amount of natural Theanine. That said these are anecdotal and could very likely be the placebo effect.
- deleted 14y ago[deleted]
- volkk 14y agoAbsolutely agreed. I've been drinking coffee for about 3-4 years now on and off, but for long periods. One cup of coffee has always been enough to have me wired for quite a while.