I think that for your example of having problems with HiDPI you might have had in mind another desktop environment than XFCE. I have been using XFCE for more t

I think that for your example of having problems with HiDPI you might have had in mind another desktop environment than XFCE. I have been using XFCE for more than 10 years almost exclusively with multiple HiDPI monitors. After Linux installation I never had to do anything else except of going to XFCE/Settings/Appearance and set a suitably high value for "Custom DPI Setting". Besides that essential setting (which scales the fonts of all applications, except for a few Java programs written by morons), it may be desirable to set a more appropriate value in "Desktop/Icons/Icon size". Also in "Panel preferences" you may want to change the size of the taskbar and the size of its icons. You may have to also choose a suitable desktop theme, but that is a thing that you may want to do after any installation, regardless of having HiDPI monitors.