3 ms·
FQ toxicity is likey caused by SNP in a specific gene related to pharmaceutical metabolism (one of the CYP450s). I believe this was published in the literature.
by monkburger 2y ago
FQ toxicity is likey caused by SNP in a specific gene related to pharmaceutical metabolism (one of the CYP450s). I believe this was published in the literature.
Another possibility is that FQ toxicity is caused by certain genes relating to detoxifying (GSH, COMT, etc) - where the body incorrectly metabolises it, leading to toxicity against cells.
- itchyouch 2y agoThat's great to know. It's unfortunate that there's an insanely high number of folks in the population that are taking FQs and running into toxicity without any hope of figuring out what is going on with their bodies. It seems that it would behoove folks to be able to take the test and know whether they are safe candidates to take FQ antibiotics.