4 ms·

If you find this appealing, make sure to do it with a medical professional. If you still want to try it by yourself, read Felix Hill's suicide note first.

ray_v 2y ago
I had to do some digging, but I did find this (who knows if it's legitimate or not) https://docs.google.com/document/d/1-jBoSEVlryiX1IaSzV4vKuihDfm_LgXUznvSpl1T1kg/edit?tab=t.0#heading=h.vnjrknmu0cff https://docs.google.com/document/d/1-jBoSEVlryiX1IaSzV4vKuih...
- jdthedisciple 2y ago
  that was something:/
- dang 2y ago
  I'm sure it's legitimate. People posted it a few times to HN but it didn't get much discussion. I'm ambivalent about that. It's a fascinating, heartbreaking and gutwrenching document. But given the research on suicide (Werther Effect, etc.) it's probably best not to publicly feature it.
throw-qqqqq 2y ago
A friend of a friend took MDMA + Ketamine every weekend. K-hole doses. Developed monday-blues which turned into a sort of servere depression as he pressed on. It took a year of abstinence before he felt “normal” again. Drugs that affect the serotonine system can do this. Burnout from (repeated) overload sort of situation IIUC. I’m no doctor, but I suspect it’s extra dangerous if you’re already suffering depression. I couldn’t read the whole note. What a tragedy :'(
- golergka 2y ago
  Taking MDMA every weekend is like drinking a few glasses of hard liquor every day. Meaning, only completely delusional and uninformed people would think it won't destroy your life. Of course, many people still do it. But they are fully aware of what road they're taking.
  - siva7 2y ago
    Trust me, the drugs won't do this..
    - solumunus 2y ago
      I took MDMA every weekend and it seriously fucked me up. I was depressed for easily a year afterwards. I suspect even 15 years on I haven’t fully regained my ability to experience joy, but this is impossible to know for sure. I can’t run the counter factual and there are many other variables at play. I was a teenager when I got too deep into MDMA.
throw18376 2y ago
i generally consider myself an enemy of psychedelic advocates, because I think they want to make it effectively socially mandatory to do these drugs, which is really bad. ("sure, it's your choice what you put in your body, but a really enlightened person wouldn't be so frightened and closed-minded that they don't want to see what psychedelics can show them...") of course ketamine for depression has this giant downside risk of adverse effects and psychosis, and we should talk about it more, not just sell it as a safe miracle drug. however... safe, neutral, bland, boring well-tolerated SSRIs, also have a massive downside risk, in that they can trigger a manic episode, which in severe cases also involves psychosis. so i find myself in the position of being glad there are different depression treatments for different people, including psychedelics and dissociatives, and hopefully we can find a way to make sure people get sorted to the treatments where they are least exposed to the tail risk side effects.
- golergka 2y ago
  > i generally consider myself an enemy of psychedelic advocates, because I think they want to make it effectively socially mandatory to do these drugs, which is really bad. > ("sure, it's your choice what you put in your body, but a really enlightened person wouldn't be so frightened and closed-minded that they don't want to see what psychedelics can show them...") I'm sorry WHAT? I've been to many open airs and other events where MOST of the people around have been under the effect of psychedelic and in other drug-friendly places, and I have never hear manipulative shit like that ever. On the contrary, if I heard people talk about this drugs it was always "it worked for me but might be a bad experience for you", "be safe, don't take it if you're not sure" and "you can always have a great time here completely sober".
  - throw18376 2y ago
    i think that "we all want to get high on drugs" situations, like festivals, are actually a lot better. it's about personal choice. when i talk about psychedelic advocates, i mean the people who think that widespread use of psychedelic drugs would massively improve mental health, make people more productive and happier, etc.
ugh123 2y ago
How do you find the right "medical professional"? I spoke to a psychiatric doctor about this recently, and he literally laughed in my face and said its all bogus.
- MavisBacon 2y ago
  Find providers who don’t seem too eager to give you as many treatments as possible. I’m getting ketamine infusions for pain through a pain specialist but he also treats depressed patients. A pain specialist may be able to help you as much as someone focused on psychiatry as they still know the drug well and often know how to treat depression

ray_v 2y ago

I had to do some digging, but I did find this (who knows if it's legitimate or not) https://docs.google.com/document/d/1-jBoSEVlryiX1IaSzV4vKuihDfm_LgXUznvSpl1T1kg/edit?tab=t.0#heading=h.vnjrknmu0cff https://docs.google.com/document/d/1-jBoSEVlryiX1IaSzV4vKuih...

jdthedisciple 2y ago
that was something:/
dang 2y ago
I'm sure it's legitimate. People posted it a few times to HN but it didn't get much discussion. I'm ambivalent about that. It's a fascinating, heartbreaking and gutwrenching document. But given the research on suicide (Werther Effect, etc.) it's probably best not to publicly feature it.

throw-qqqqq 2y ago

A friend of a friend took MDMA + Ketamine every weekend. K-hole doses. Developed monday-blues which turned into a sort of servere depression as he pressed on. It took a year of abstinence before he felt “normal” again. Drugs that affect the serotonine system can do this. Burnout from (repeated) overload sort of situation IIUC. I’m no doctor, but I suspect it’s extra dangerous if you’re already suffering depression. I couldn’t read the whole note. What a tragedy :'(

golergka 2y ago
Taking MDMA every weekend is like drinking a few glasses of hard liquor every day. Meaning, only completely delusional and uninformed people would think it won't destroy your life. Of course, many people still do it. But they are fully aware of what road they're taking.
- siva7 2y ago
  Trust me, the drugs won't do this..
  - solumunus 2y ago
    I took MDMA every weekend and it seriously fucked me up. I was depressed for easily a year afterwards. I suspect even 15 years on I haven’t fully regained my ability to experience joy, but this is impossible to know for sure. I can’t run the counter factual and there are many other variables at play. I was a teenager when I got too deep into MDMA.

throw18376 2y ago

i generally consider myself an enemy of psychedelic advocates, because I think they want to make it effectively socially mandatory to do these drugs, which is really bad. ("sure, it's your choice what you put in your body, but a really enlightened person wouldn't be so frightened and closed-minded that they don't want to see what psychedelics can show them...") of course ketamine for depression has this giant downside risk of adverse effects and psychosis, and we should talk about it more, not just sell it as a safe miracle drug. however... safe, neutral, bland, boring well-tolerated SSRIs, also have a massive downside risk, in that they can trigger a manic episode, which in severe cases also involves psychosis. so i find myself in the position of being glad there are different depression treatments for different people, including psychedelics and dissociatives, and hopefully we can find a way to make sure people get sorted to the treatments where they are least exposed to the tail risk side effects.

golergka 2y ago
> i generally consider myself an enemy of psychedelic advocates, because I think they want to make it effectively socially mandatory to do these drugs, which is really bad. > ("sure, it's your choice what you put in your body, but a really enlightened person wouldn't be so frightened and closed-minded that they don't want to see what psychedelics can show them...") I'm sorry WHAT? I've been to many open airs and other events where MOST of the people around have been under the effect of psychedelic and in other drug-friendly places, and I have never hear manipulative shit like that ever. On the contrary, if I heard people talk about this drugs it was always "it worked for me but might be a bad experience for you", "be safe, don't take it if you're not sure" and "you can always have a great time here completely sober".
- throw18376 2y ago
  i think that "we all want to get high on drugs" situations, like festivals, are actually a lot better. it's about personal choice. when i talk about psychedelic advocates, i mean the people who think that widespread use of psychedelic drugs would massively improve mental health, make people more productive and happier, etc.

ugh123 2y ago

How do you find the right "medical professional"? I spoke to a psychiatric doctor about this recently, and he literally laughed in my face and said its all bogus.

MavisBacon 2y ago
Find providers who don’t seem too eager to give you as many treatments as possible. I’m getting ketamine infusions for pain through a pain specialist but he also treats depressed patients. A pain specialist may be able to help you as much as someone focused on psychiatry as they still know the drug well and often know how to treat depression