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For anyone wondering why genetic data (e.g. alphabet: ATCGU) is compressed as gzip and not as .bwt.gz, its because it's a costly operation to run on a whole gen
by tetris11 2y ago
For anyone wondering why genetic data (e.g. alphabet: ATCGU) is compressed as gzip and not as .bwt.gz, its because it's a costly operation to run on a whole genome pre-compression, and makes it impossible to chunk (e.g. if you're interested in a limited locus, you now have to find all related bases to that locus, and perform the unrotation + decompression).
It's got some limited use in mapping though, and suffix arrays are still dead useful in non-BWT mappers