3 ms·

The atherosclerosis is invisible, until it suddenly isn't. Everyone will have a little bit of plaque, even if you try to eat well. Teenagers will already have

by tux3 2y ago

The atherosclerosis is invisible, until it suddenly isn't. Everyone will have a little bit of plaque, even if you try to eat well. Teenagers will already have traces of it before they reach adulthood. All you can do is try to slow down the buildup. And, well, this ain't it.

pipes 2y ago
Genuine question, as far as I can tell there seems to be some debate currently about weather high saturated fat diets are linked with heart disease. Does atherosclerosis fall into this debate too?
- KempyKolibri 2y ago
  Yes, high SFA diets are associated with increased risk of CVD via atherosclerosis as a result of the increase in ApoB concentration in the blood (response to retention hypothesis). This review paper is a really good overview of the model, and it's actually pretty approachable: https://academic.oup.com/eurheartj/article/41/24/2313/5735221 https://academic.oup.com/eurheartj/article/41/24/2313/573522...
  - pipes 2y ago
    Thanks
FooBarBizBazz 2y ago
I suppose that's true normally, but I was pleased to read that you can probably reverse it if you make radical enough changes: https://www.health.harvard.edu/heart-health/ask_the_doctor_is_it_possible_to_reverse_coronary_artery_disease https://www.health.harvard.edu/heart-health/ask_the_doctor_i...
- tux3 2y ago
  ... where "radical enough change" in this article refers to the period of starvation during WW2! My understanding is that we don't have contemporary evidence of people successfully reverting arterial plaque, but I admit the studies probably didn't faithfully reproduce these starvation conditions!
  - KempyKolibri 2y ago
    There’s some evidence of a reduction of intima-media thickness of both common carotid arteries through a… less intense diet. https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.120.033214 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.120.0...
    - tux3 2y ago
      Thank you. Seems like between this and other results, the consensus is now that reversal has been demonstrated pretty conclusively. I've updated!
  - hulitu 2y ago
    Gaza ? /s

by tux3 2y ago

pipes 2y ago

Genuine question, as far as I can tell there seems to be some debate currently about weather high saturated fat diets are linked with heart disease. Does atherosclerosis fall into this debate too?

KempyKolibri 2y ago
Yes, high SFA diets are associated with increased risk of CVD via atherosclerosis as a result of the increase in ApoB concentration in the blood (response to retention hypothesis). This review paper is a really good overview of the model, and it's actually pretty approachable: https://academic.oup.com/eurheartj/article/41/24/2313/5735221 https://academic.oup.com/eurheartj/article/41/24/2313/573522...
- pipes 2y ago
  Thanks

FooBarBizBazz 2y ago

I suppose that's true normally, but I was pleased to read that you can probably reverse it if you make radical enough changes: https://www.health.harvard.edu/heart-health/ask_the_doctor_is_it_possible_to_reverse_coronary_artery_disease https://www.health.harvard.edu/heart-health/ask_the_doctor_i...

tux3 2y ago
... where "radical enough change" in this article refers to the period of starvation during WW2! My understanding is that we don't have contemporary evidence of people successfully reverting arterial plaque, but I admit the studies probably didn't faithfully reproduce these starvation conditions!
- KempyKolibri 2y ago
  There’s some evidence of a reduction of intima-media thickness of both common carotid arteries through a… less intense diet. https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.120.033214 https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.120.0...
  - tux3 2y ago
    Thank you. Seems like between this and other results, the consensus is now that reversal has been demonstrated pretty conclusively. I've updated!
- hulitu 2y ago
  Gaza ? /s