Yes, there are serious drug interactions that can occur with MDMA. The one I’m most familiar with is not to take MDMA if you also take any MAOI, which is listed

Yes, there are serious drug interactions that can occur with MDMA. The one I’m most familiar with is not to take MDMA if you also take any MAOI, which is listed in that article. Being hospitalized would certainly lead to a bad trip, in my opinion.