Well... we will lose handwriting ability, and also the ability to read handwritten texts, but we have already (almost) substitute such abilities with something

Well... we will lose handwriting ability, and also the ability to read handwritten texts, but we have already (almost) substitute such abilities with something more efficient. This means than on one side we "popularize" things before "to far from common people knowledge" while we live more room for different skilled people in more specific segments of the human knowledge. This means that cognitive abilities have to change, as are always changed through history. We will have some "generic workers" able to do something like small potatoes IT, data science, architectural design etc, without really much competences and few who decide to dig something and acquire skills "like in the past". I see not much difference in the old adage "with the printed books we will lose the real knowledge and epistemological skills", it was a bit true indeed, but back then 99% of the people was even unable to read, after a sizeable amount of people acquire poor but still present reading skills, and some still remain knowledgeable anyway. I expect in the future not very cultured people been able to do stuff now done only by few, while still some will be really cultured like today.