In short, yes. There have been quite a few studies that show that low fat diets have no bearing on developing heart disease. But here is the rub. Most studies

In short, yes. There have been quite a few studies that show that low fat diets have no bearing on developing heart disease. But here is the rub. Most studies that show X,Y, and Z lead to heart disease are observational epidemiological studies. This means that researchers collect data from a number of disparate sources and attempt to make sense of it. The problem is that it is very hard to tease out confounding variables. So I don't put much stock in this type of study. They have their value, but I wouldn't make any life decisions off of them. Their primary purpose is to help formulate hypotheses that can be tested experimentally. When it comes to experimental tests, the lipid hypothesis has been shown to be wrong over and over. On the contrary, quite a bit of experimental data shows that a grain based, low fat, high carbohydrate increases the markers for heart disease.