A nuclear reactor could suffice as a local power source. Maybe fusion in another 50 years. With a local power source, electrolytic oxygen generation is possible

A nuclear reactor could suffice as a local power source. Maybe fusion in another 50 years. With a local power source, electrolytic oxygen generation is possible. Food, hydroponics. Transportation? Could figure something out. Most of this tech is stuff we already have or developed with NASA/etc for the ISS gearing it up as a self sustainment environment. Main problem would be internal volume.