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No-hole surgery: no keyhole, yet surgeons can now still operate under your skin (2023)
- noisy_boy 2y agotldr; they use a transducer (a gun that uses focused ultrasound) to solidify a special ink (injected beforehand) which is ultrasound and temperature sensitive allowing them to create solid structures/implants of desired shape
- rkagerer 2y agoAnd they used the technique to demo a mock surgery inside a heart removed from a goat (left atrial appendage closure - basically seals off a portion susceptible to blood clots).
- duchef 2y agoAtrial appendage occlusions are already performed without surgery via endovascular access from the groin.
- lostlogin 2y agoNot sure what counts as surgery for everyone here, but having my femoral artery punctured counts if a <X>ologist does it to me.
- choilive 2y agothat is definitely a surgical procedure done by a surgeon.. hrm
- duchef 2y agoNo, it's a procedure performed by an interventional cardiologist - who is not a surgeon.
- fastball 2y agoReminds me of vasalgel for male birth control.
- anonu 2y agoThis is fascinating - but the HN headline could be more informative: 3D printing technique builds structures through tissues would suffice.
- mmooss 2y agoAgreed. To clarify, the OP's own headline is: Getting under your skin: 3D printing technique builds structures through tissues
- MeteorMarc 2y ago(2023)
- aniijbod 2y agoYes, the original headline was actually pretty good
- jijji 2y agoI think the bigger idea behind this research, which was not mentioned, is the fact that the pointing of the the multiple beams directed by the transducer can not only be used to heat up a specific point inside the body (which in their example was an "ink" that was used for creating 3D structures well below the tissue), but the fact that this could be used for things like removal of plaques, blockages, destruction of fat/lipid cells in vivo... So things like stents and angioplasty's which are currently used to open up clogged arteries in cardiac patients to prevent heart attacks, could be done in vivo, the same way they are describing in the article, but without the need to use an "ink"... So this technology definitely has multiple uses. It could also be used to target plaques in brain tissue embedded deep in the brain to directly remove amyloid plaques to treat dementia, depression, etc patients...Obviously also used to target tumor cells anywhere inside the body without using chemotherapy/radiation.
- mmooss 2y agoThat is interesting, but where does it come from? It's not in the OP or in the research paper, at least not in the summary, abstract, or conclusion, or in other parts I skimmed. https://www.science.org/doi/10.1126/science.adi1563 https://www.science.org/doi/10.1126/science.adi1563
- slt2021 2y agothis reminds me of Intensity-modulated radiation therapy (IMRT) - a treatment of cancer using X-ray beams. because a single beam damages both healthy and cancer tissue alike (and goes through entire body like jedi's lightsaber), IMRT creates many many low dosage beams around the body from different angles. As a result, most of healthy tissue that surrounds tumor gets exposed to a minimum radiation, but cancerous tissue accumulates required x-ray exposure from many small beams.
- chiph 2y agoThey already do this to treat some kinds of Parkinson's https://www.youtube.com/watch?v=XNk3UF488mg https://www.youtube.com/watch?v=XNk3UF488mg
- aniijbod 2y ago
- from-nibly 2y ago> The world of medicine would be transformed Look I know I'm being obtuse, and a Dingus, but I'm so tired of the silly hype. It wouldn't transform the whole world of medicine. It would maybe change a small part of specific surgeries. I've never had an implant surgery and I do take pills and other medicines daily. It would affect implant surgeries, it would not affect my vitamin d pill.
- lionkor 2y agoIt's got 3 minute papers vibes. What a time to be alive!!!
- aniijbod 2y agoI've seen what appear to me to be far less deserving papers get the same kind of perhaps excessively exuberant hype, but in this case, it's not looking quite that far off the mark, IMO
- throw5959 2y agoMaybe this will lead to a new kind of surgery that will allow you to stop taking pills.
- from-nibly 2y agoHow? This paper is so far off from anything like that. This kind of blind optimism is part of what gets to me.
- throw5959 2y agoEh, are you sure? I don't think you can say it so decisively. I am not saying it will be a direct result - but one of the steps.
- seanhunter 2y agoAgree. For example I’ve had 3 surgeries in the last couple of years. It would not affect/improve any of them. In one, robotic surgery[1] was used but they needed to take stuff out rather than put new structures in. In the other two, keyhole surgery was used and they needed to cut/grind stuff away rather than add something new. It might well be that certain surgeries would be significantly improved but not all. [1] https://www.intuitive.com/en-us/products-and-services/da-vinci/5 https://www.intuitive.com/en-us/products-and-services/da-vin... this is the thing they used, which is a genuinely amazing gadget and reminds me of the Hokkaido mission from “Hitman”.
- mometsi 2y agoI'm no topologist, but I don't think they're going to be able to place that catheter without at least one hole.
- deleted 2y ago[deleted]
- wizardforhire 2y agoOh theres a hole, it’s just not the one you’d think of inserting something into… rule 33 aside.
- deleted 2y ago[deleted]
- mmooss 2y agoHere is the paper. Xiao Kuang et al. Self-enhancing sono-inks enable deep-penetration acoustic volumetric printing. Science 382, 1148-1155 (2023) https://www.science.org/doi/10.1126/science.adi1563 https://www.science.org/doi/10.1126/science.adi1563
- adrian_b 2y agoAnd here is downloadable version of the paper: https://www.researchgate.net/publication/376308676_Self-enhancing_sono-inks_enable_deep-penetration_acoustic_volumetric_printing https://www.researchgate.net/publication/376308676_Self-enha...
- mmooss 2y ago(2023)
- crumpled 2y agoI dislike the name "ink" for a plastic or resin compound with which we are going to saturate regions of our bodies. It reminds me of George Carlin talking about euphemisms.
- gsmethells 2y agoCould they 3D print in such a way as to make pre-fabricated joint implants a thing of the past?
- aniijbod 2y agoI think that the nature of the thing that was needing to be implanted would determine whether it was easier and safer to use a traditional incision. Hip replacements for instance use a titanium joint. However, seeing as the bone that it is replacing was not made of titanium, somehow nature has found a way to make bone strong enough to do the job. There is an important sense in which nature 'builds things using 3D printing' and does it without needing incisions, so even if we do manage to master doing 3D printing under the skin the way we do it now to an extent where we can replace things that currently need materials that are not suited to under skin 3D printing...
- praveen9920 2y agoIt will be interesting to see such techniques for normal 3d printing without support structures.
- aniijbod 2y agoAny ideas on what that would be like?
- praveen9920 2y agoI heard about some resin 3d printers that work inside a resin instead of open air so that they don't need support.
- jamesholden 2y agoSorry to send dense, but it says No-hole surgery. How then, is the 'ink' delivered to the right location for this to work?
- koliber 2y agoMy guess is through an injection. Calling a needle injection site a surgery hole is excessively pedantic. A normal person would not call a vaccine injection or a blood test "surgery."
- deleted 2y ago[deleted]