Your comment makes no sense. Every mirrorless body has a center marking for the middle of the sensor, so the camera can be mounted exactly centered on a tripod

Your comment makes no sense. Every mirrorless body has a center marking for the middle of the sensor, so the camera can be mounted exactly centered on a tripod. It's actually important for photos to be exactly on axis if you want to do panoramas or stitching. The only reason the body is not exactly symmetrical is engineering and ergonomics. Many point and shoots of the past in fact had the lens exactly in the center. And "chirality of the optical path" is not anything related to this, in fact the term is not usable in this context at all.