This was used as a plot point in The Abyss (1989). The rats in that movie were actually breathing Fluorinert, but they used special effects for the human actors

This was used as a plot point in The Abyss (1989). The rats in that movie were actually breathing Fluorinert, but they used special effects for the human actors. The Abyss also may have inspired the use of LCL as a breathing fluid in Evangelion.