4 ms·
Switch to unflavored. The flavorings likely act as MAO inhibitors and synergistically boost the neurological effects of nicotine which by itself is not signific
by cluckindan 2y ago
Switch to unflavored. The flavorings likely act as MAO inhibitors and synergistically boost the neurological effects of nicotine which by itself is not significantly addictive (but can be habit-forming for some people).
Exception to the rule is menthol flavoring. Menthol is a kappa opioid agonist. In the nervous system, it produces dysphoria — opposite of euphoria, i.e. feeling bleak, anxious, depressed. This effect lasts longer than nicotine’s effect, leading to redosing.