Patriot batteries have shot down every missile type that isn't an IRBM like Oreshnik, and those are closer to Mach 11 than Mach 5. Kinzhal and Zircon have been

Patriot batteries have shot down every missile type that isn't an IRBM like Oreshnik, and those are closer to Mach 11 than Mach 5. Kinzhal and Zircon have been at least semi-reliably shot down. Iskander is very reliablly shot down. The main issue is that Ukraine just doesn't have enough Patriot batteries to defend the whole country, so the Russians stopped shooting where the air defense is. They also use a bunch of S-300s as ballistic missiles (a secondary capability to their primary role as air defense) but primarily against cities that don't have air defense. But they're too inaccurate and inexpensive for the Ukrainians to bother attempting to intercept even if they had enough of the appropriate air defenses.