3 ms·
I’ve read numerous anecdotal accounts that espouse this. Not discounting yours at all, as the precise mechanism of action of modafinil is not well understood de
by alphan0n 2y ago
I’ve read numerous anecdotal accounts that espouse this. Not discounting yours at all, as the precise mechanism of action of modafinil is not well understood despite decades of human testing [0][1]. From my limited understanding, it increases histamine, the effect opposite of anti-histamines like diphenhydramine.
[0]https://pubmed.ncbi.nlm.nih.gov/15991923/ https://pubmed.ncbi.nlm.nih.gov/15991923/
[1]https://pubmed.ncbi.nlm.nih.gov/22640618/ https://pubmed.ncbi.nlm.nih.gov/22640618/
Anecdotally, despite being a very subtle effect, in my specific set of circumstances, modafinil has been life changing.
- ipaddr 2y agoIf all it is doing is adding histamine could you get it from food?
- alphan0n 2y agoPresumably, modafinil causes production and continual release of histamine via mast cells in quantities far greater and faster than the most histamine rich foods. Fermented fish tops the list, which, personally, sounds profoundly unappealing for breakfast. But to each their own, maybe a cup of coffee and a can of surströmming is the ultimate morning combo