There are libraries that communicate with screen readers of every platform. Of course, you need to think where the text comes from and all so it scales with you

There are libraries that communicate with screen readers of every platform. Of course, you need to think where the text comes from and all so it scales with your app, but it really is a non issue in the end. (edit: focusing in text having "meaning" and being spoken here. As it is very often I see this question about immediate mode GUIs. Of course there are other things about accessibility, but they're more of a design question rather than technology.)