Glaucoma is due to the gradual death of retinal ganglion cells. The cause of death is often metabolic stress caused by axonal damage near the lamina cribrosa (w

Glaucoma is due to the gradual death of retinal ganglion cells. The cause of death is often metabolic stress caused by axonal damage near the lamina cribrosa (where fibers exit the eye). High dose nicotinamide prevents some types if glaucoma in mice by improving the metabolic resilience of mitochondria and retinal ganglion cells.