3 ms·
Curiously there are around 6 cases reported in India in the recent years, with varying degree of confidence in the diagnosis. With 20000 confirmed death per yea
by alexey-salmin 2y ago
Curiously there are around 6 cases reported in India in the recent years, with varying degree of confidence in the diagnosis. With 20000 confirmed death per year in India, this could mean that survival rate is in fact 0.01% and not 0.00%, it just looks the same unless you have a huge sample.
Another interesting question is: how many people get infected, then recover, but never develop the symptoms? Do they exist? Could it even be common? On that question, the chances of developing symptoms after a confirmed rabid bite are estimated to be between 15% and 60%. What exactly happens to other 40%? Does the virus fails to get hold and multiply? Or on the contrary it's not stealthy enough and triggers the immune response that defeats it? Or it starts to spread and then stops for some other reason? And whatever happens, what exactly determines it: truly random chance, or genes of the infected person or variant of the virus or type of the bite?
Currently we identify rabies with the terminal stage of the disease and the only reliable test is posthumous, so no wonder it's 100% deadly. While it's indeed extremely deadly it's still a curious question of how much exactly this "extremely" means: 60% or 99.99% or 100%.
Probably this will never be studied, because the humane way is to conduct none of that research and just vaccinate every suspected person within reach. Plus where possible try to eradicate infection reservoirs like the did in the Alps in 1970s. These 20000 people in India could've lived, it's a shame really.
- apple4ever 2y agoReally good point about whether there are cases where the immune system catches it early or the virus can't survive for another reason.
- tzs 2y ago> Another interesting question is: how many people get infected, then recover, but never develop the symptoms? Do they exist? It appears so [1]: “New research has shown that humans may be able to survive Rabies without vaccination or treatment after all. A study done in Peru (were Vampire Bats, a known Rabies carrier, are common) lead by Amy Gilbert of the U.S. Centers for Disease Control and Prevention found that 7 out of the 63 people evaluated tested positive for rabies antibodies. Of those seven people only one had previously taken the Rabies vaccine. This meant that the other six had produced antibodies on their own after being exposed to the virus and had survived.” [1] https://www.nature.com/scitable/blog/viruses101/is_rabies_really_100_fatal/ https://www.nature.com/scitable/blog/viruses101/is_rabies_re...