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Here's a talk by someone from Gilead from a few years ago about how it works.[1] Back then they were still testing on animals. It's amazing that a small-molecu
by Animats 2y ago
Here's a talk by someone from Gilead from a few years ago about how it works.[1] Back then they were still testing on animals.
It's amazing that a small-molecule drug can be that effective for six months. It's not a vaccine. It doesn't stimulate the immune system. Completely different mechanism. It's not a slow-release implanted thing, either.
[1] https://www.youtube.com/watch?v=Hmjn_7TeFUA https://www.youtube.com/watch?v=Hmjn_7TeFUA
- allenjhyang 2y agoReally cool. Is the mechanism already used for other diseases? Or is this a first-of-its-kind application that'll open the door to using the mechanism for others?
- lightedman 2y agoThat is what got me. How in the world does this drug have such a long life in the body? Can it bioaccumulate, and that's why it's only given every 6 months? If it can, are there effects that are not desirable?