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> Unlike DNA, which assumes a simple double-stranded helix, RNA adopts a diverse array of intramolecular structural features including hairpins DNA can conform
by akira2501 2y ago
> Unlike DNA, which assumes a simple double-stranded helix, RNA adopts a diverse array of intramolecular structural features including hairpins
DNA can conform to a simple helix but it's absolutely not stored or utilized in that conformation in vivo. DNA also adopts a diverse array of particular _local_ configurations based upon it's own electro-chemical gradients combined with those of the cellular environment it inhabits.
> Many ribozymes cleave co-transcriptionally and so cannot be purchased outright as RNA, otherwise they may cleave upon deblocking and/or dissolving in buffer.
That's kinda funny. Also part of the reason RNA world looks so convincing.
- nomel 2y agoI wonder what percent of "junk" DNA is there just to mediate "viable" local configurations?