Codons for the same amino acid can have very different efficiencies due to use of different tRNAs. And tRNA abundance varies across organelles (mitochondria), c

Codons for the same amino acid can have very different efficiencies due to use of different tRNAs. And tRNA abundance varies across organelles (mitochondria), cells, and organs. It is not just protein sequence but also protein abundance and translational progressivity/speed/efficiency and completeness. Reverse translation would not recover these aspects.