3 ms·
Muscles also have more than one nucleus per cell, if you have strength trained. You can fast and diet and waste away all the protein and shrink them down, but t
by kridsdale1 2y ago
Muscles also have more than one nucleus per cell, if you have strength trained. You can fast and diet and waste away all the protein and shrink them down, but the nuclei remain. Go in to a surge of calories, protein, (and optional androgenic hormone signaling) and the nuclei effectively parallel process transcription of mRNA in the ribosomes for regeneration of the proteins from amino acids and re-bulking up of the cells and your strength.
This, (along with neural adaption) is what we are taking about when we reference “muscle memory”. It’s a steep hill to
train the first time and multiply the nuclei, but once you have them, you have them for life, and subsequent re-strengthening efforts will be far easier.
I’ve gone through this myself and it’s pretty shocking. It took me X years to achieve Y kilograms barbell whatever movement. A diet or lack of training for a year and I can only do Y/2. But if I eat a ton, I can be back to Y or higher in a few months.
- renewiltord 2y agoThat’s the mechanism? It makes sense. It was trivial for me to return to my strength after an accident that left me hobbled for months but progress beyond is just as hard as originally. Cool.
- eru 2y agoThat's part of the mechanism.
- jjtheblunt 2y agoThe fusion of single nucleus myoblasts into multi nuclei myofibers is clear at this link...quite neat https://en.wikipedia.org/wiki/Myogenesis https://en.wikipedia.org/wiki/Myogenesis