5 ms·
So, the more spike protein, the worse the symptoms, but also vaccination with Pfizer/BioNTech reduced the number of spike proteins stuck in the marrow. I wonder
by abracadaniel 2y ago
So, the more spike protein, the worse the symptoms, but also vaccination with Pfizer/BioNTech reduced the number of spike proteins stuck in the marrow. I wonder why mRNA making more spike proteins improves the situation
- birdiesanders 2y agoThe Moderna spike and the Pfizer spike are both “inflated” by edits to the gene that cause some different arrangements of the protein structure that causes the spike to be more rigid and closer to the shape it has when embedded on the virus surface. I imagine that there is some threshold where something too thin or too small begins to be hard to clean up, and the vaccine-induced spikes are above that line, while the natural spikes detached from the virus are under. I’m a computer person so probably not correct, but I’m not blindly guessing, either.
- abracadaniel 2y agoIt’s things like this that constantly remind me that biology is far more complex in practice, and even while having a deeper understanding than most, I’m relying on some very grossly oversimplified abstractions.
- thenerdhead 2y agoMore antibodies against spike protein, T cells have an idea of what to respond to, and less IL-6 cytokines meaning less inflammation.