3 ms·

Because HPV vaccination is relatively modern, there's trail where maybe the trial for the vaccine you can get today A, was A vs B, but then the previous B has a

Because HPV vaccination is relatively modern, there's trail where maybe the trial for the vaccine you can get today A, was A vs B, but then the previous B has a trial B v Placebo, or it might go back twice, A v B then B v C and C v placebo. There were placebo trials for the early HPV vaccines decades ago. I had Hodgkins Lymphoma (many years ago now when I was young) and we've been treating that for so long that the earliest curative treatments pre-date scientific medicine. So the trail dries up - we have no proof that the cures are better than nothing except, you know, circumstantially it sure does seem like the freaks who reject treatment just drop dead and I didn't so... They're still doing research, as with the HPV vaccines they do A v B trials as a placebo would be unethical - it's basically a death sentence. I actually wasn't selected for a trial comparing Stanford V (a new potential therapy from Stanford) against the current gold standard (which I was getting) ABVD. That was a long time ago, but I think the gold standard today is still ABVD.

User23 2y ago
Calling cervical cancer a death sentence is a bit extreme. Regular pap smears and early treatment made it eminently survivable.
- wbl 2y ago
  You can detect melanoma with the eyes. But when you don't get there early enough it was game over. Now it's a coin flip.
- Spooky23 2y ago
  It’s a big deal. “Survivable” means intrusive treatment that is painful, not always effective and has side effects on things like fertility. Or you can eliminate it by vaccination and avoid the suffering and risk.
- tialaramex 2y ago
  I can see how you'd end up with that interpretation but I was actually talking about Hodgkins, so in that case the placebo arm would in fact be basically a death sentence. You've got an aggressive cancer, and you've decided (or your treatment arm has decided) to just let it take its course.

User23 2y ago

Calling cervical cancer a death sentence is a bit extreme. Regular pap smears and early treatment made it eminently survivable.

wbl 2y ago
You can detect melanoma with the eyes. But when you don't get there early enough it was game over. Now it's a coin flip.
Spooky23 2y ago
It’s a big deal. “Survivable” means intrusive treatment that is painful, not always effective and has side effects on things like fertility. Or you can eliminate it by vaccination and avoid the suffering and risk.
tialaramex 2y ago
I can see how you'd end up with that interpretation but I was actually talking about Hodgkins, so in that case the placebo arm would in fact be basically a death sentence. You've got an aggressive cancer, and you've decided (or your treatment arm has decided) to just let it take its course.