3 ms·

You might be interested in epigenetic inheritence. We do know that some epigenetic marks are passed down but its still very much unknown how much heritable info

by aydyn 2y ago

You might be interested in epigenetic inheritence. We do know that some epigenetic marks are passed down but its still very much unknown how much heritable information is encoded in epigenetics.

PittleyDunkin 2y ago
While histones and methylation aren't DNA themselves, they're certainly incapable of functioning without DNA. I'd assume the parent poster was referring to further still mechanics.
westurner 2y ago
Transgenerational epigenetic inheritance: https://en.wikipedia.org/wiki/Transgenerational_epigenetic_inheritance https://en.wikipedia.org/wiki/Transgenerational_epigenetic_i... Methods of intergenerational transfer: DNA, RNA, bacteria, fungi, verbal latencies, explicit training From https://x.com/westurner/status/1213675095513878528 https://x.com/westurner/status/1213675095513878528 : > Does the fundamental limit of the amount of classical information encodable in the human genome (even with epigenetics & simultaneous encoding) imply a vast capacity for learning survival-beneficial patterns in very little time, with very few biasing priors? > [Fundamental 'gbit' requirement 1: “No Simultaneous Encoding”:] if a gbit is used to perfectly encode one classical bit, it cannot simultaneously encode any further information. Two close variants of this are Zeilinger’s Principle (10) and Information Causality (11). > Is there a proved presumption that genes only code in sequential combinations? Still overestimating the size of the powerset of all [totally-ordered] nonlocal combinations? Still trying to understand counterfactuals in re: constructor theory Constructor theory: https://en.wikipedia.org/wiki/Constructor_theory https://en.wikipedia.org/wiki/Constructor_theory (quantum) Counterfactuals reasoning: https://www.google.com/search?q=(quantum)+*Counterfactual*+reasoning+reasons https://www.google.com/search?q=(quantum)+*Counterfactual*+r... : > Counterfactual reasoning is the process of considering events that could have happened but didn't. Counterfactual definiteness: https://en.wikipedia.org/wiki/Counterfactual_definiteness https://en.wikipedia.org/wiki/Counterfactual_definiteness Quantum discord; there are multiple types of quantum entropy; entanglement and non-entanglement entropy: https://en.wikipedia.org/wiki/Quantum_discord https://en.wikipedia.org/wiki/Quantum_discord N-ary entanglement, Collective unconscious > See also: https://en.wikipedia.org/wiki/Collective_unconscious https://en.wikipedia.org/wiki/Collective_unconscious FWIU memories are stored in the cortex and also in the hippocampus; "Brain found to store three copies of every memory" (2024) https://news.ycombinator.com/item?id=41352124 https://news.ycombinator.com/item?id=41352124
- westurner 2y ago
  ... How do dogs know what not to eat in the wild?
  - andsoitis 2y ago
    > ... How do dogs know what not to eat in the wild? They don’t.
    - westurner 2y ago
      Then how have any survived? Observe the human response to dandelions; are they weeds or are they edible? Do they have lobed leaves? What [neurons,] do mammals have to heuristically generalize according to visual and gustatory-olfactory features, and counterfactually which don't they have? Or it's entirely learned, and then the coding for the substrate is still relevant

by aydyn 2y ago

You might be interested in epigenetic inheritence. We do know that some epigenetic marks are passed down but its still very much unknown how much heritable information is encoded in epigenetics.

PittleyDunkin 2y ago

While histones and methylation aren't DNA themselves, they're certainly incapable of functioning without DNA. I'd assume the parent poster was referring to further still mechanics.

westurner 2y ago

Transgenerational epigenetic inheritance: https://en.wikipedia.org/wiki/Transgenerational_epigenetic_inheritance https://en.wikipedia.org/wiki/Transgenerational_epigenetic_i... Methods of intergenerational transfer: DNA, RNA, bacteria, fungi, verbal latencies, explicit training From https://x.com/westurner/status/1213675095513878528 https://x.com/westurner/status/1213675095513878528 : > Does the fundamental limit of the amount of classical information encodable in the human genome (even with epigenetics & simultaneous encoding) imply a vast capacity for learning survival-beneficial patterns in very little time, with very few biasing priors? > [Fundamental 'gbit' requirement 1: “No Simultaneous Encoding”:] if a gbit is used to perfectly encode one classical bit, it cannot simultaneously encode any further information. Two close variants of this are Zeilinger’s Principle (10) and Information Causality (11). > Is there a proved presumption that genes only code in sequential combinations? Still overestimating the size of the powerset of all [totally-ordered] nonlocal combinations? Still trying to understand counterfactuals in re: constructor theory Constructor theory: https://en.wikipedia.org/wiki/Constructor_theory https://en.wikipedia.org/wiki/Constructor_theory (quantum) Counterfactuals reasoning: https://www.google.com/search?q=(quantum)+*Counterfactual*+reasoning+reasons https://www.google.com/search?q=(quantum)+*Counterfactual*+r... : > Counterfactual reasoning is the process of considering events that could have happened but didn't. Counterfactual definiteness: https://en.wikipedia.org/wiki/Counterfactual_definiteness https://en.wikipedia.org/wiki/Counterfactual_definiteness Quantum discord; there are multiple types of quantum entropy; entanglement and non-entanglement entropy: https://en.wikipedia.org/wiki/Quantum_discord https://en.wikipedia.org/wiki/Quantum_discord N-ary entanglement, Collective unconscious > See also: https://en.wikipedia.org/wiki/Collective_unconscious https://en.wikipedia.org/wiki/Collective_unconscious FWIU memories are stored in the cortex and also in the hippocampus; "Brain found to store three copies of every memory" (2024) https://news.ycombinator.com/item?id=41352124 https://news.ycombinator.com/item?id=41352124

westurner 2y ago
... How do dogs know what not to eat in the wild?
- andsoitis 2y ago
  > ... How do dogs know what not to eat in the wild? They don’t.
  - westurner 2y ago
    Then how have any survived? Observe the human response to dandelions; are they weeds or are they edible? Do they have lobed leaves? What [neurons,] do mammals have to heuristically generalize according to visual and gustatory-olfactory features, and counterfactually which don't they have? Or it's entirely learned, and then the coding for the substrate is still relevant