I think there are plenty of diseases where people would be willing to roll the dice on low probability unintended consequences if it meant a massive 100% probab

I think there are plenty of diseases where people would be willing to roll the dice on low probability unintended consequences if it meant a massive 100% probability life improvement. This research is great because it reduces our uncertainty about the former option. That said, I wouldn't wanna be the first person to do elective CRISPR therapy for something that I don't actually need (i.e. LASIK, etc).