It's a fascinating topic, isn't it? The hydrogen exhaust in nuclear thermal rockets isn't actually radioactive (well, in practice it was, because the rockets t

It's a fascinating topic, isn't it? The hydrogen exhaust in nuclear thermal rockets isn't actually radioactive (well, in practice it was, because the rockets they actually built had a tendency to fall apart and eject bits of their nuclear fuel in the exhaust, but on paper that shouldn't happen). But the power-plant versions are closed gas loops anyway—you're driving the hydrogen or helium through a turbine, it's a sealed system. I don't think you'd choose to build any serious containment building on Mars. The baseline risk of death on Mars is extremely high; nuclear accident risks don't appreciably move the needle. My understanding is what you'd actually do is put a biological shield—maybe a pile of Martian rock—on the line-of-sight between the reactor and the astronaut base, and, simply, never walk that way. Cooling is substantially easier on Mars than in space, since there's an atmosphere that functions as a heat sink. The space version (i.e., in the nuclear electric propulsion context) has a more difficult challenge, with radiation as the sole heat dissipation mechanism. You're right that a space reactor would have to be designed for zero maintenance, else it'd be a non-starter.