It strongly depends on the quantities you're dealing with. From the sounds if it you're working at low volumes, so you're not likely to get much of a response f

It strongly depends on the quantities you're dealing with. From the sounds if it you're working at low volumes, so you're not likely to get much of a response from the manufacturers themselves. Instead, you're basically gonna be working with the big suppliers like digikey, mouser, etc. You can get a quote for a BOM from them, and sometimes that'll be a discount, but also in general you're gonna be spending a lot more on overhead of organising/setting up/building a board than you are on the components for a small volume run.