4 ms·
This study is just awful. Can we stop funding epidemiological studies with little to no reproducibility? At least use more frequent objective sleep measurements
by bottom999mottob 2y ago
This study is just awful. Can we stop funding epidemiological studies with little to no reproducibility? At least use more frequent objective sleep measurements, and account for confounding variables.
- They openly acknowledge they "can't say that poor sleep causes dementia" aka they established a correlation but no direction of causality
- There's self-reporting bias where participants were "asked about" their sleep patterns
- There's selection and survival bias: the participants were around 40 y/o, the ones that remained for 10 years might be different than those who dropped
- The sample was for a cardiovascular disease study
- They didn't control for unmeasured confounders other than "age, sex, education, health and lifestyle factors"
- The 1.6-2.6 years of brain aging were measured using ML algorithms and this is a small enough effect to be within a margin of error...