I am obligated do my usual unpopular reply that people are not calorimeters, the type of food and the cadence matters a lot and perhaps even more than the quant

I am obligated do my usual unpopular reply that people are not calorimeters, the type of food and the cadence matters a lot and perhaps even more than the quantity. Humans are very complex organisms made up of many other complex organisms that react in very complex ways to food and each other. The effect of hormones dominate the caloric expenditure to the point that sufficient hormone intervention can be impossible to overcome with any amount of eating. I think the desire to simplify the model down to calorie in and calorie out is a way of putting all responsibility onto the unhealthy individual as an aversion to empathy. Our population has been intentionally misinformed and our food has been poisoned in a way that personal responsibility cannot always overcome, so while people may still deserve the brunt of the blame we must also understand that the food industry/medical/politics played a substantial part in creating the situation and as hard as it is to fight back against these profitable industries it is even more difficult to remodel people to have more willpower.