All the psychedelic substances which produce their activity through interactions with the serotonin 5-HT2A - mescaline, LSD, psilocybin, and DMT in particular -

All the psychedelic substances which produce their activity through interactions with the serotonin 5-HT2A - mescaline, LSD, psilocybin, and DMT in particular - are largely banned by governments and their production, distribution and use all have varying criminal charges associated in most countries and regions. These drugs are generally much less addictive than alcohol, nicotine, opiates, and amphentamines, drugs which are considered to have medical uses of some sort and are not criminalized as energetically as the psychedelics, which is a bit odd. I suppose if you want an orderly obedient population not given to asking difficult questions of the established authoritarians (such as 'why are we paying you taxes that you use to live in a big mansion with lots of servants'), then you might be concerned about psychedelic use for reasons having nothing to do with medicine. You might be afraid of losing control, of random ideas popping up and spreading through the population, a questioning of long-established social norms, etc. I really wonder if that's where the control freak hysteria on this topic comes from.