4 ms·
Cerebrospinal fluid is produced in the brain, I would imagine that the contrast would end up in newly produced fluid as well, but maybe that assumption is wrong
by elric 2y ago
Cerebrospinal fluid is produced in the brain, I would imagine that the contrast would end up in newly produced fluid as well, but maybe that assumption is wrong.
- sithadmin 2y agoEven assuming that the contrast could show up in newly excreted CSF (maybe, maybe not), MRI contrast elimination half lives are very short (mostly all under ~2 hrs, excepting cases like renal dysfunction), and cerebrospinal fluid doesn’t replenish particularly quickly.
- physPop 2y agoUnfortunately no, that is not how the contrast agent gets around. Most Gd agents are huge and don’t leak out of the vasculature unless there is a disruption (tumour etc).