> A shred of evidence is the ratio of proposed drugs by academics and the drugs that can enter a phase III clinical trial as they have shown some efficacy. It's

> A shred of evidence is the ratio of proposed drugs by academics and the drugs that can enter a phase III clinical trial as they have shown some efficacy. It's something like 1000 to 1. A shred of evidence of what? It sounds like the output of an extremely large effort that hasn’t panned out yet, which is obviously true.