3 ms·
We are slowly learning that our immune system is the key to longevity. Many articles these last few years on ways to renew it, ways to treat dysfunction, and t
by thenerdhead 2y ago
We are slowly learning that our immune system is the key to longevity.
Many articles these last few years on ways to renew it, ways to treat dysfunction, and the common bad guys we really need to remove from our bodies as they are directly linked to currently incurable diseases like T1D, MS, Alzheimer’s, Parkinson’s, ME/CFS, Long COVID, and more.
It seems very realistic we may cure/reverse disease course for a handful of these within the next decade at this rate. Many novel clinical trials are happening to probe at the causes and if proven, we could have new drugs quickly due to the pandemic forcing supply chains to be able to meet antigen targets.
- voisin 2y ago> the common bad guys we really need to remove from our bodies Can you elaborate?
- thenerdhead 2y agoOver the last four years we have made tremendous progress in identifying pathogenic antigens as the main culprit in these diseases. Some may be caused by undetected low grade chronic infections and some may be lingering antigens causing constant immune system activation / dysfunction.
- aashu_dwivedi 2y agocan you elaborate what are the medical trials which are going on for this?
- DJBunnies 2y agoI’m skeptical it has basis in medicine, but I’m here to see too.
- thenerdhead 2y agohttps://www.nature.com/articles/s41392-024-01911-3 https://www.nature.com/articles/s41392-024-01911-3 https://www.nature.com/articles/s41531-024-00716-z https://www.nature.com/articles/s41531-024-00716-z https://www.nature.com/articles/d41586-024-00470-5 https://www.nature.com/articles/d41586-024-00470-5 https://www.science.org/content/article/long-covid-trials-aim-clear-lingering-virus-help-patients-need https://www.science.org/content/article/long-covid-trials-ai... https://videocast.nih.gov/watch=54970 https://videocast.nih.gov/watch=54970 https://www.nature.com/articles/d41586-024-00871-6 https://www.nature.com/articles/d41586-024-00871-6 https://www.nature.com/articles/d41586-024-01274-3 https://www.nature.com/articles/d41586-024-01274-3 https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-treatment-adults-alzheimers-disease https://www.fda.gov/drugs/news-events-human-drugs/fda-approv... Immunotherapy is entering the golden age and we're about to find out what and what doesn't work.
- FollowingTheDao 2y agoBut what controls the immune system? IMO it is oxidative imbalance that dis-regulates the immune system, leading to a hyper or hypo inflammatory state. That is, autoimmunity or immunodeficiency.
- thenerdhead 2y agoIt's more nuanced than that. genetic predisposition (immune/HLA genes working or not), infections (potential for antigen persistence), diet, environmental factors, stress, etc all also contribute heavily.