Thank you for telling the story. To me, it’s interesting to consider the inflammatory aspects – the immunomodulatory effects of LSD and other psychedelics on o

Thank you for telling the story. To me, it’s interesting to consider the inflammatory aspects – the immunomodulatory effects of LSD and other psychedelics on one hand and alcohol on the other. It’s well established but little-known that psychedelics have a very significant inflammation-reducing effect which includes drastic reduction of neuroinflammation. (I’m fairly sure that this is a primary reason why they work for depression and anxiety; There’s basically always elevated inflammatory biomarkers with these disorders. Stress is directly causative of neuroimflammation.) Here’s a really solid review paper from 2017 – today a lot more knowledge has been accumulated: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2015.00358/full https://www.frontiersin.org/journals/immunology/articles/10.... Alcohol is known to be pro-inflammatory. I have a hunch that these two disjoint forces on the same physiological systems can have made things worse.