3 ms·

In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people not caring about their long term effects but only on

by arijo 2y ago

In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people not caring about their long term effects but only on profit. I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings.

cthalupa 2y ago
> In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people Drugs lose their patents and much of the research on novel medications is done in partnerships with universities, etc. Plenty of other scientists unrelated to the drug companies are continuing research through entirely separate funding. But I guess everyone is in the pocket of big pharma? > not caring about their long term effects but only on profit. What long term effects? You still haven't elucidated any concerns. > I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings. You can find plenty of them on instagram, youtube, and tiktok. They'll be happy to sell you another fitness device and Yet Another Protein Powder or a pill made out of some plant extract that has minimal to no scientific evidence of efficacy.
- arijo 2y ago
  Every drug has long term side effects but people are being sold GLP1 as a miracle weight lost pill when the focus should be on reducing all the toxic junk food that is causing the weight gain in the first place. And yes, many research programs are funded by pharma - the conlict of interests is blatant and getting more people sicker every year. Honestly, I’m pretty sure you’re very aware of all this so I question your motivations to be openly promoting a drug that interferes directly with cellular metabolism like if you’re selling candy.
  - cthalupa 2y ago
    You're still not providing any sort of claim as to what actual negative side effects you are concerned about, so I don't really know how to have a serious conversation with you. "Interfering with cellular metabolism" is a meaningless phrase. Please provide some sort of method of action that you are actually concerned about. What is it that it is doing to cells that we should be concerned about? What scientific evidence is there that this action is unhealthy?
    - arijo 2y ago
      I'm unfortunately expecting this getting worse with massive adoption of the drug but we can start with "Risk of Suicidal Thoughts and thoughts of self-harm with medicines known as GLP-1 receptor agonists,1 including Ozempic (semaglutide), Saxenda (liraglutide) and Wegovy (semaglutide)" - https://www.ema.europa.eu/en/news/ema-statement-ongoing-review-glp-1-receptor-agonists https://www.ema.europa.eu/en/news/ema-statement-ongoing-revi... By the way - why are you so eager to promote this drug - can you please declare any conflict of interests?
      - cthalupa 2y ago
        > By the way - why are you so eager to promote this drug - can you please declare any conflict of interests? The closest thing to a conflict of interest I have is that I am currently seeing great results while taking tirzepatide. I find it significantly easier to choose healthier meals made of whole foods with balanced macros, to eat less in general, and to motivate myself to push back towards the exercise habits I had in my 20s. I have no relation to big pharma, and I have no idea if my index fund tracking retirement plans include Novo Nordisk or Eli Lilly, but if they do, that's the closest thing I have to a financial incentive in these companies doing well. > we can start with "Risk of Suicidal Thoughts and thoughts of self-harm with medicines known as GLP-1 receptor agonists,1 including Ozempic (semaglutide), Saxenda (liraglutide) and Wegovy (semaglutide)" Please read the content you are linking. It said that there were some reports so they were beginning to perform a review. The article specifically mentions the review was set to conclude in Nov 2023. Upon seeing this, I figured it would be a good idea to see if the results of the review had come out. It took me one google query to find the results: https://www.ema.europa.eu/en/news/meeting-highlights-pharmacovigilance-risk-assessment-committee-prac-8-11-april-2024 https://www.ema.europa.eu/en/news/meeting-highlights-pharmac... > The PRAC has concluded that the available evidence does not support a causal association between the Glucagon-Like Peptide-1 receptor agonists (GLP-1) – dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide – and suicidal and self-injurious thoughts and actions. So we can scratch that one off the list.
  - deleted 2y ago
    [deleted]
navjack27 2y ago
Wow... instead of ever more metabolic and mentally ill society living more like zombies than free human beings. Literally just wow. What possesses you to say such a horrible thing?
- arijo 2y ago
  Possess is a strong word - nevertheless you can start here if you want to be aware of what is going on in the real world: Youtube Videos https://youtu.be/PeqQd4_xveI?t=43 https://youtu.be/PeqQd4_xveI?t=43 https://youtu.be/G0lTyhvOeJs?t=421 https://youtu.be/G0lTyhvOeJs?t=421 https://www.youtube.com/@metabolicmind https://www.youtube.com/@metabolicmind Books https://a.co/d/cUAgokV https://a.co/d/cUAgokV https://a.co/d/32zSKzo https://a.co/d/32zSKzo https://a.co/d/acVla0y https://a.co/d/acVla0y
- theshackleford 2y ago
  Mental health treatment is not as widely available as it should be.

by arijo 2y ago

cthalupa 2y ago

> In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people Drugs lose their patents and much of the research on novel medications is done in partnerships with universities, etc. Plenty of other scientists unrelated to the drug companies are continuing research through entirely separate funding. But I guess everyone is in the pocket of big pharma? > not caring about their long term effects but only on profit. What long term effects? You still haven't elucidated any concerns. > I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings. You can find plenty of them on instagram, youtube, and tiktok. They'll be happy to sell you another fitness device and Yet Another Protein Powder or a pill made out of some plant extract that has minimal to no scientific evidence of efficacy.

arijo 2y ago
Every drug has long term side effects but people are being sold GLP1 as a miracle weight lost pill when the focus should be on reducing all the toxic junk food that is causing the weight gain in the first place. And yes, many research programs are funded by pharma - the conlict of interests is blatant and getting more people sicker every year. Honestly, I’m pretty sure you’re very aware of all this so I question your motivations to be openly promoting a drug that interferes directly with cellular metabolism like if you’re selling candy.
- cthalupa 2y ago
  You're still not providing any sort of claim as to what actual negative side effects you are concerned about, so I don't really know how to have a serious conversation with you. "Interfering with cellular metabolism" is a meaningless phrase. Please provide some sort of method of action that you are actually concerned about. What is it that it is doing to cells that we should be concerned about? What scientific evidence is there that this action is unhealthy?
  - arijo 2y ago
    I'm unfortunately expecting this getting worse with massive adoption of the drug but we can start with "Risk of Suicidal Thoughts and thoughts of self-harm with medicines known as GLP-1 receptor agonists,1 including Ozempic (semaglutide), Saxenda (liraglutide) and Wegovy (semaglutide)" - https://www.ema.europa.eu/en/news/ema-statement-ongoing-review-glp-1-receptor-agonists https://www.ema.europa.eu/en/news/ema-statement-ongoing-revi... By the way - why are you so eager to promote this drug - can you please declare any conflict of interests?
    - cthalupa 2y ago
      > By the way - why are you so eager to promote this drug - can you please declare any conflict of interests? The closest thing to a conflict of interest I have is that I am currently seeing great results while taking tirzepatide. I find it significantly easier to choose healthier meals made of whole foods with balanced macros, to eat less in general, and to motivate myself to push back towards the exercise habits I had in my 20s. I have no relation to big pharma, and I have no idea if my index fund tracking retirement plans include Novo Nordisk or Eli Lilly, but if they do, that's the closest thing I have to a financial incentive in these companies doing well. > we can start with "Risk of Suicidal Thoughts and thoughts of self-harm with medicines known as GLP-1 receptor agonists,1 including Ozempic (semaglutide), Saxenda (liraglutide) and Wegovy (semaglutide)" Please read the content you are linking. It said that there were some reports so they were beginning to perform a review. The article specifically mentions the review was set to conclude in Nov 2023. Upon seeing this, I figured it would be a good idea to see if the results of the review had come out. It took me one google query to find the results: https://www.ema.europa.eu/en/news/meeting-highlights-pharmacovigilance-risk-assessment-committee-prac-8-11-april-2024 https://www.ema.europa.eu/en/news/meeting-highlights-pharmac... > The PRAC has concluded that the available evidence does not support a causal association between the Glucagon-Like Peptide-1 receptor agonists (GLP-1) – dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide – and suicidal and self-injurious thoughts and actions. So we can scratch that one off the list.
- deleted 2y ago
  [deleted]

navjack27 2y ago

Wow... instead of ever more metabolic and mentally ill society living more like zombies than free human beings. Literally just wow. What possesses you to say such a horrible thing?

arijo 2y ago
Possess is a strong word - nevertheless you can start here if you want to be aware of what is going on in the real world: Youtube Videos https://youtu.be/PeqQd4_xveI?t=43 https://youtu.be/PeqQd4_xveI?t=43 https://youtu.be/G0lTyhvOeJs?t=421 https://youtu.be/G0lTyhvOeJs?t=421 https://www.youtube.com/@metabolicmind https://www.youtube.com/@metabolicmind Books https://a.co/d/cUAgokV https://a.co/d/cUAgokV https://a.co/d/32zSKzo https://a.co/d/32zSKzo https://a.co/d/acVla0y https://a.co/d/acVla0y
theshackleford 2y ago
Mental health treatment is not as widely available as it should be.