Uxn uses big endian primarily because it is meant to be easily assembled from (or disassembled into) a thin programming language called Tal. I think Tal is mean

Uxn uses big endian primarily because it is meant to be easily assembled from (or disassembled into) a thin programming language called Tal. I think Tal is meant to be the highest-level language available in this platform, so it should be as convenient as possible without being too fat---`#1234` in Tal would ideally be assembled to two bytes `12 34` therefore.