> You can't prepare for acclimatization, and you don't know how well your body will handle it before actually going up there. This is something of an enduring

> You can't prepare for acclimatization, and you don't know how well your body will handle it before actually going up there. This is something of an enduring medical mystery despite efforts to find related genes, etc. I think part of it is the compounding of second order effects, like who can say whether individual performance one week into an expedition will be more affected by bad sleep, bad digestion, or bad headaches? If one is immune to some side effects, how long before the others really take a toll? The team member who is strongest one day may be weakest the next depending on how the schedule of different kinds of attrition and reserves all line up, so it’s really hard to predict in advance without some direct experience. Even then it’s a moving target as we train or age.