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You're really conflating things. Altman is no Hassabis. Just because there is a ton of hype from OpenAI doesn't detract from what DeepMind has done. AlphaGo an
by FrustratedMonky 2y ago
You're really conflating things. Altman is no Hassabis.
Just because there is a ton of hype from OpenAI doesn't detract from what DeepMind has done. AlphaGo anybody?
Are we really already forgetting what a monumental problem protein folding was, decades of research, and AlphaFold came in and revolutionized it overnight.
We are pretty jaded these days when miracles are happening all the time and people are like "yeah, but he's just a manager 'now', what have they done for me in the last few days".
- authorfly 2y agoI am missing context here and would love to know more. Say I know about ATP Synthase and how the proteins/molecules involved there interact to make a sort of motor. How does AlphaFold help us understand that or more complicated systems? Are proteins quite often dispersed and unique, finding each other to interact with? Or like ATP Synthase are they more of a specific blueprint which tends to arrange in the same way but in different forms? In other words: Situation 1) Are there many ATP synthase type situations we find too complex to understand - regular patterns and regular co-occurences of proteins but we don't understand them? Situation 2) Or is most of the use of Protein situational and one-off? We see proteins only once or twice, very complicated ones, yet they do useful things? I struggle to situate the problem of Unknown proteins without knowing which of the above two is true (and why?)
- chermi 2y agoNitpick - this is protein structure prediction, not protein folding
- FrustratedMonky 2y agoIsn't the folding how the structure is created?