Tirzepatide (aka Zepbound/Mounjaro) is called a dual-action GLP-1/GIP agonist. The GLP-1 action overall makes you feel less hungry, basically. The GIP action sl

Tirzepatide (aka Zepbound/Mounjaro) is called a dual-action GLP-1/GIP agonist. The GLP-1 action overall makes you feel less hungry, basically. The GIP action slows gastric emptying (how quickly food moves from your stomach to your small intenstine) so you feel full longer. It also has a modest effect on lipolysis, which means it does help somewhat in breaking down adipose tissue (fat) to use for energy more efficiently. Semaglutide is a GLP-1 agonist only. Retratutide is a newer drug that is triple-action. Generally on these drugs the action does not induce more "calorie burning", they are used mostly to modulate caloric intake. >I don't know how to feel about the idea that we need treatment for being overweight in general. Obesity is by orders of magnitude the worst public health issue facing humanity. Obesity makes every disease worse. Obese people are more likely to develop cancer, cardiovascular issues, respiratory issues, dementia, diabetes, and other afflictions. Obesity often leads to depression, lack of motivation, lower libidos, overall worse moods in general. Of course there are "levels" to it, it's not to say everyone has to be a bodybuilder to be happy and healthy. Of course not. This is not about being slightly overweight, or "wanting to lose 15 lbs for summer"... But in almost every way, being fat makes life worse for the majority of people.