4 ms·
> Something that can model heart rate and blood pressure won't be able to say if a cancer drug will work (or if it will have a toxic side effect) Thanks for ha
by JPLeRouzic 2y ago
> Something that can model heart rate and blood pressure won't be able to say if a cancer drug will work (or if it will have a toxic side effect)
Thanks for having a look at Biogears.
(edit) Please have a look at:
"Constraint-based modelling predicts metabolic signatures of low and high-grade serous ovarian cancer"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344801/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344801/
https://github.com/katemeeson/repository_to_accompany_paper_2023 https://github.com/katemeeson/repository_to_accompany_paper_...
Most successful pre-clinical trials *fail* at predicting phase III success. The ratio is enormous. It's time to put some effort into alternative approaches.