5 ms·

The Role of Childhood Trauma in Psychosis and Schizophrenia: A Systematic Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858420/ https://www.ncbi.nlm.nih.

by rendx 2y ago

The Role of Childhood Trauma in Psychosis and Schizophrenia: A Systematic Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858420/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858420/ "Childhood Trauma is probably the most important environmental factor associated with Schizophrenia. There is evidence of multiple paths between traumatic experiences and psychosis. Mental disorders are systems of interacting symptoms through a framework of networks. Psychotic symptoms in patients with a history of child abuse are more severe, persistent, and refractory to treatment. In developmental years, exposure to neglect and abuse reveals severe adverse effects on the average neurobiological growth, leading to vulnerable neurobiology preceding disadvantageous psychiatric outcomes." https://www.theguesthouseocala.com/understanding-the-connection-between-schizophrenia-and-trauma/ https://www.theguesthouseocala.com/understanding-the-connect... "The guiding principles of trauma-specific care can give you the space to uncover the root of your schizophrenia and trauma. Thus, understanding how your early traumas have impacted you opens the door to dismantling maladaptive coping mechanisms. As you deepen your self-understanding, it encourages you to lean into adaptive coping strategies to process your experiences and life stressors. Furthermore, with support, you can find a path to recovery from schizophrenia and trauma that considers you and your specific experiences."

rendx 2y ago
Schlesselmann, A. J., Huntjens, R. J., Renard, S. B., McNally, R. J., Albers, C. J., De Vries, V. E., & Pijnenborg, G. H. (2022). A Network Approach to Trauma, Dissociative Symptoms, and Psychosis Symptoms in Schizophrenia Spectrum Disorders. Schizophrenia Bulletin https://doi.org/10.1093/schbul/sbac122 https://doi.org/10.1093/schbul/sbac122 "Ccongruent with the idea of an association between stressful life events and dissociative experiences, research has established a link between the presence and severity of dissociation and reported interpersonal traumas such as sexual, physical, and emotional abuse, with multiple traumas being linked to more severe symptoms. In SSD populations up to 60% of individuals report a history of interpersonal trauma. The core explanation for the mechanism linking trauma and symptoms of SSD states that trauma leads to a vulnerability rendering the individual susceptible to the experience of perceptual and sensory intrusions. In line with the idea of trauma as a vulnerability factor for psychotic as well as for dissociative symptoms, studies have shown that more frequent dissociative and more severe psychotic symptoms in SSD are linked to reported trauma in a dose-response relationship."
throw18376 2y ago
i'm getting very argumentative on the internet today (under a pseudonymous account because as you might guess from my incessant posting, this issue is personal for me) trauma (at any time), drug use, other experiences -- all can make schizophrenia more likely in those susceptible. absolutely true. but it is a biological disease, and healing trauma won't stop its progression. as your source notes, the trauma causes differences in brain development, and once that's done its done. i don't think coming up with a new drug, the main advantage of which is it doesn't numb you the horrible way existing antipychotics do, is a bad thing. this is basically a drug that was only created to improve the QoL of people with schizophrenia. if society just wanted to numb them, we already have drugs for that and could just be much more aggressive in violently coercing treatment. investing in these drugs isn't "looking away", it's putting in a huge investment of many billions of dollars to help the victims live better lives.
- rendx 2y ago
  > once that's done its done "As such, the hippocampus and hippocampal neuroplasticity may also play a key role in resilience and recovery from stress. This is supported by the current finding that hippocampal volume increased following psychological therapy." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943737/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943737/ "we found a significant [hippocampal] volume expansion during a 12-week treatment period, which correlated with clinical improvement" https://www.biologicalpsychiatryjournal.com/article/S0006-3223(13)00471-X/fulltext https://www.biologicalpsychiatryjournal.com/article/S0006-32... Increased hippocampal volume and gene expression following cognitive behavioral therapy in PTSD https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2013.00747/full https://www.frontiersin.org/journals/human-neuroscience/arti...
  - creatonez 2y ago
    No one mentioned PTSD?
    - rendx 2y ago
      I did! When you look at the studies I posted initially, one theory is that schizophrenia is a result of posttraumatic stress caused by childhood trauma, and a coping strategy (flashbacks, intrusions, dissociation). It may not be in all cases, but in the cases where that is, PTSD treatment seems to work to fundamentally heal schizophrenia. Remission of schizophrenia after an EMDR session https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820797/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820797/ Applications of Trauma Treatment for Schizophrenia https://www.tandfonline.com/doi/full/10.1080/10926771003705114 https://www.tandfonline.com/doi/full/10.1080/109267710037051... Making meaning of trauma in psychosis https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1272683/full https://www.frontiersin.org/journals/psychiatry/articles/10.... Even if you believe schizophrenia to be first and then lead to traumatic experiences (which it certainly will), it makes total sense to do a trauma assessment and heal the maladaptive strategies and broken beliefs related to these traumatic experiences, which is where again PTSD treatment comes in. "In the last 2 decades, it has become obvious that child abuse, urbanization, migration, and adverse life events contribute to the etiology of schizophrenia and other psychoses. […] I expect to see the end of the concept of schizophrenia soon." (Murray, R. M. (2016). Mistakes I Have Made in My Research Career. Schizophrenia Bulletin, sbw165. doi:10.1093/schbul/sbw165)
gosub100 2y ago
> with support, you can find a path to recovery from schizophrenia They misspelled "medication". There are narrow situations where very skilled psychiatrists have successfully treated schizophrenics using non-pharma (read: traditional) psychotherapy, but they are truly exceptional cases. Being schizophrenic is not a lack of "deepening your self-understanding" that blocks them from "uncovering the root of " their illness! That is absolutely horse shit and belongs in a new age Homeopathy boutique. Schizophrenics firmly believe their delusions and paranoia. In fact, one of the worst things you can say to them is "it's all in your head! The voices aren't real!". Commonly, they split the world into allies and suspects, so the moment you try to invalidate them, they add you to the list of agents/spirits/whatever is after them. This disease requires a psychiatrist and medication, full stop, and is fully orthogonal to child abuse.
- rendx 2y ago
  Hardy, A., Keen, N., van den Berg, D., Varese, F., Longden, E., Ward, T., & Brand, R. M. (2023). Trauma therapies for psychosis: A state‐of‐the‐art review. Psychology and Psychotherapy: Theory, Research and Practice. https://doi.org/10.1111/papt.12499 https://doi.org/10.1111/papt.12499 Schäfer, I., & Fisher, H. L. (2022). Childhood trauma and psychosis-what is the evidence? Dialogues in clinical neuroscience. P. 360 – 365. https://doi.org/10.31887/DCNS.2011.13.2/ischaefer https://doi.org/10.31887/DCNS.2011.13.2/ischaefer Schlesselmann, A. J., Huntjens, R. J., Renard, S. B., McNally, R. J., Albers, C. J., De Vries, V. E., & Pijnenborg, G. H. (2022). A Network Approach to Trauma, Dissociative Symptoms, and Psychosis Symptoms in Schizophrenia Spectrum Disorders. Schizophrenia Bulletin https://doi.org/10.1093/schbul/sbac122 https://doi.org/10.1093/schbul/sbac122 etc.
  - rendx 2y ago
    Onyeama, F., Melegkovits, E., Yu, N., Parvez, A., Rodrigues, A., Billings, J., ... & Bloomfield, M. A. (2024). A systematic review and meta-analysis of the traumatogenic phenotype hypothesis of psychosis. BJPsych Open, 10(5), e146. https://doi.org/10.1192/bjo.2024.52 https://doi.org/10.1192/bjo.2024.52 "there is evidence of a causal relationship between developmental trauma and psychosis, including clear temporal sequences between exposure and outcome, plausible mechanisms and dose–response relationships"

by rendx 2y ago

rendx 2y ago

Schlesselmann, A. J., Huntjens, R. J., Renard, S. B., McNally, R. J., Albers, C. J., De Vries, V. E., & Pijnenborg, G. H. (2022). A Network Approach to Trauma, Dissociative Symptoms, and Psychosis Symptoms in Schizophrenia Spectrum Disorders. Schizophrenia Bulletin https://doi.org/10.1093/schbul/sbac122 https://doi.org/10.1093/schbul/sbac122 "Ccongruent with the idea of an association between stressful life events and dissociative experiences, research has established a link between the presence and severity of dissociation and reported interpersonal traumas such as sexual, physical, and emotional abuse, with multiple traumas being linked to more severe symptoms. In SSD populations up to 60% of individuals report a history of interpersonal trauma. The core explanation for the mechanism linking trauma and symptoms of SSD states that trauma leads to a vulnerability rendering the individual susceptible to the experience of perceptual and sensory intrusions. In line with the idea of trauma as a vulnerability factor for psychotic as well as for dissociative symptoms, studies have shown that more frequent dissociative and more severe psychotic symptoms in SSD are linked to reported trauma in a dose-response relationship."

throw18376 2y ago

i'm getting very argumentative on the internet today (under a pseudonymous account because as you might guess from my incessant posting, this issue is personal for me) trauma (at any time), drug use, other experiences -- all can make schizophrenia more likely in those susceptible. absolutely true. but it is a biological disease, and healing trauma won't stop its progression. as your source notes, the trauma causes differences in brain development, and once that's done its done. i don't think coming up with a new drug, the main advantage of which is it doesn't numb you the horrible way existing antipychotics do, is a bad thing. this is basically a drug that was only created to improve the QoL of people with schizophrenia. if society just wanted to numb them, we already have drugs for that and could just be much more aggressive in violently coercing treatment. investing in these drugs isn't "looking away", it's putting in a huge investment of many billions of dollars to help the victims live better lives.

rendx 2y ago
> once that's done its done "As such, the hippocampus and hippocampal neuroplasticity may also play a key role in resilience and recovery from stress. This is supported by the current finding that hippocampal volume increased following psychological therapy." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943737/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943737/ "we found a significant [hippocampal] volume expansion during a 12-week treatment period, which correlated with clinical improvement" https://www.biologicalpsychiatryjournal.com/article/S0006-3223(13)00471-X/fulltext https://www.biologicalpsychiatryjournal.com/article/S0006-32... Increased hippocampal volume and gene expression following cognitive behavioral therapy in PTSD https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2013.00747/full https://www.frontiersin.org/journals/human-neuroscience/arti...
- creatonez 2y ago
  No one mentioned PTSD?
  - rendx 2y ago
    I did! When you look at the studies I posted initially, one theory is that schizophrenia is a result of posttraumatic stress caused by childhood trauma, and a coping strategy (flashbacks, intrusions, dissociation). It may not be in all cases, but in the cases where that is, PTSD treatment seems to work to fundamentally heal schizophrenia. Remission of schizophrenia after an EMDR session https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820797/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820797/ Applications of Trauma Treatment for Schizophrenia https://www.tandfonline.com/doi/full/10.1080/10926771003705114 https://www.tandfonline.com/doi/full/10.1080/109267710037051... Making meaning of trauma in psychosis https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1272683/full https://www.frontiersin.org/journals/psychiatry/articles/10.... Even if you believe schizophrenia to be first and then lead to traumatic experiences (which it certainly will), it makes total sense to do a trauma assessment and heal the maladaptive strategies and broken beliefs related to these traumatic experiences, which is where again PTSD treatment comes in. "In the last 2 decades, it has become obvious that child abuse, urbanization, migration, and adverse life events contribute to the etiology of schizophrenia and other psychoses. […] I expect to see the end of the concept of schizophrenia soon." (Murray, R. M. (2016). Mistakes I Have Made in My Research Career. Schizophrenia Bulletin, sbw165. doi:10.1093/schbul/sbw165)

gosub100 2y ago

> with support, you can find a path to recovery from schizophrenia They misspelled "medication". There are narrow situations where very skilled psychiatrists have successfully treated schizophrenics using non-pharma (read: traditional) psychotherapy, but they are truly exceptional cases. Being schizophrenic is not a lack of "deepening your self-understanding" that blocks them from "uncovering the root of " their illness! That is absolutely horse shit and belongs in a new age Homeopathy boutique. Schizophrenics firmly believe their delusions and paranoia. In fact, one of the worst things you can say to them is "it's all in your head! The voices aren't real!". Commonly, they split the world into allies and suspects, so the moment you try to invalidate them, they add you to the list of agents/spirits/whatever is after them. This disease requires a psychiatrist and medication, full stop, and is fully orthogonal to child abuse.

rendx 2y ago
Hardy, A., Keen, N., van den Berg, D., Varese, F., Longden, E., Ward, T., & Brand, R. M. (2023). Trauma therapies for psychosis: A state‐of‐the‐art review. Psychology and Psychotherapy: Theory, Research and Practice. https://doi.org/10.1111/papt.12499 https://doi.org/10.1111/papt.12499 Schäfer, I., & Fisher, H. L. (2022). Childhood trauma and psychosis-what is the evidence? Dialogues in clinical neuroscience. P. 360 – 365. https://doi.org/10.31887/DCNS.2011.13.2/ischaefer https://doi.org/10.31887/DCNS.2011.13.2/ischaefer Schlesselmann, A. J., Huntjens, R. J., Renard, S. B., McNally, R. J., Albers, C. J., De Vries, V. E., & Pijnenborg, G. H. (2022). A Network Approach to Trauma, Dissociative Symptoms, and Psychosis Symptoms in Schizophrenia Spectrum Disorders. Schizophrenia Bulletin https://doi.org/10.1093/schbul/sbac122 https://doi.org/10.1093/schbul/sbac122 etc.
- rendx 2y ago
  Onyeama, F., Melegkovits, E., Yu, N., Parvez, A., Rodrigues, A., Billings, J., ... & Bloomfield, M. A. (2024). A systematic review and meta-analysis of the traumatogenic phenotype hypothesis of psychosis. BJPsych Open, 10(5), e146. https://doi.org/10.1192/bjo.2024.52 https://doi.org/10.1192/bjo.2024.52 "there is evidence of a causal relationship between developmental trauma and psychosis, including clear temporal sequences between exposure and outcome, plausible mechanisms and dose–response relationships"