Nukes aren't a perfect model for a ship full of explosive fertilizer, but a reasonable enough approximation/upper bound for which we can easily find formulas/ca

Nukes aren't a perfect model for a ship full of explosive fertilizer, but a reasonable enough approximation/upper bound for which we can easily find formulas/calculators online. A 15 kiloton nuke has a 1 psi radius of about 3 km according to https://nuclearsecrecy.com/nukemap/# https://nuclearsecrecy.com/nukemap/# So a possible solution would indeed be stopping it by any means necessary somewhere between the 22 km mark (where it enters territorial waters) and the 3 km mark where it becomes a serious hazard.