3 ms·

By all means, eat as much healthy food as you can afford. But whatever caused your psychiatric problems, it couldn't have been food. Unless you're so poor that

By all means, eat as much healthy food as you can afford. But whatever caused your psychiatric problems, it couldn't have been food. Unless you're so poor that you severely malnourished, or you're eating something severely toxic. And even then, lots of places in this world with malnourished populations that are not depressed. Improving the quality of your life is not just food. It's all the other things that go into it. Like autonomy, sense of security, friends, social status, finances, physical activity levels, etc. So be sure to look after improving those things too. And my suggestion for walking a dog, is a simple and practical suggestion for something that will get you both companionship and exercise. From personal experience, quitting smoking helped with anxiety. That longing feeling for a cigarette was making me anxious, and that feeling would persist even after having one. So quitting was helpful. But again, smoking is not eating.

FollowingTheDao 2y ago
> By all means, eat as much healthy food as you can afford. But whatever caused your psychiatric problems, it couldn't have been food Are there purines, like Inosine and Guanosine, in food? Did you even ask what my genetic disorder is?
- dukeofdoom 2y ago
  I'm always open to learning things I don't know about ... go on
  - FollowingTheDao 2y ago
    Cool. I have a Partial PNP Deficiency that makes it harder for me to break down Inosine and Guanosine (and xanthine). My PNP enzyme only functions at about 12% of most "normal" people. Image: https://www.frontiersin.org/files/Articles/538247/fimmu-11-01257-HTML/image_m/fimmu-11-01257-g001.jpg https://www.frontiersin.org/files/Articles/538247/fimmu-11-0... Paper on the topic: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01257/full https://www.frontiersin.org/journals/immunology/articles/10.... So how does food affect me? They use Inosine (Inosinic acid) and Guanosine (Guanylic acid) in foods as a food additives to increase the umami. https://www.eurofins.com/media-centre/newsletters/food-newsletter-nr44-march-2014/flavour-enhancers-in-food-products/ https://www.eurofins.com/media-centre/newsletters/food-newsl... These are also found naturally in many foods: https://www.umamiinfo.com/richfood/ https://www.umamiinfo.com/richfood/ When I eat these foods I cannot break these purines down and they not only cause mood issues but also an immune deficiency. Purinergic System Dysfunction is linked to mood disorders: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262688/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262688/ After going on a low specific purine diet I no longer need any of the three psychiatric medications I was on but for klonopin since there are some triggers I cannot avoid. Food did this. Food and having a good doctor who did not give up on me. Food and knowing what my genetics are. I get that some people might benefit from Yoga, etc, but to serve a blanket statement like that is just ignorant of the genetic and environmental diversity of humanity. I have these genetics because I have Sami heritage and I am adapted to live in a cold climate and eating low purine, high zinc foods. Zinc also helps me break down the purines by stimulating LACC1, which is a sort of PNP backup. A zinc deficiency when I was young left me with an undecended testicle because of my LACC1 genetics. https://www.uniprot.org/uniprotkb/Q8IV20/entry https://www.uniprot.org/uniprotkb/Q8IV20/entry
    - seper8 2y ago
      Super interesting, thanks for sharing
    - jaggederest 2y ago
      Thank you for posting the genetic polymorphism, makes it much easier to cross reference. Glad you've found an answer!
    - dukeofdoom 2y ago
      Thank you, interesting read. My friend that has an autistic son, wants to cure him through diet changes. Do you know anything food related to autism?
      - FollowingTheDao 2y ago
        Not really, but this may be a good start: Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935591/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935591/ and https://www.mdpi.com/2218-1989/10/5/184 https://www.mdpi.com/2218-1989/10/5/184 I do not think the spectrum of autism are caused by a single gene or environmental factor. I was diagnosed with Asperger's as well, much too late in life.

FollowingTheDao 2y ago

> By all means, eat as much healthy food as you can afford. But whatever caused your psychiatric problems, it couldn't have been food Are there purines, like Inosine and Guanosine, in food? Did you even ask what my genetic disorder is?

dukeofdoom 2y ago
I'm always open to learning things I don't know about ... go on
- FollowingTheDao 2y ago
  Cool. I have a Partial PNP Deficiency that makes it harder for me to break down Inosine and Guanosine (and xanthine). My PNP enzyme only functions at about 12% of most "normal" people. Image: https://www.frontiersin.org/files/Articles/538247/fimmu-11-01257-HTML/image_m/fimmu-11-01257-g001.jpg https://www.frontiersin.org/files/Articles/538247/fimmu-11-0... Paper on the topic: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01257/full https://www.frontiersin.org/journals/immunology/articles/10.... So how does food affect me? They use Inosine (Inosinic acid) and Guanosine (Guanylic acid) in foods as a food additives to increase the umami. https://www.eurofins.com/media-centre/newsletters/food-newsletter-nr44-march-2014/flavour-enhancers-in-food-products/ https://www.eurofins.com/media-centre/newsletters/food-newsl... These are also found naturally in many foods: https://www.umamiinfo.com/richfood/ https://www.umamiinfo.com/richfood/ When I eat these foods I cannot break these purines down and they not only cause mood issues but also an immune deficiency. Purinergic System Dysfunction is linked to mood disorders: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262688/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262688/ After going on a low specific purine diet I no longer need any of the three psychiatric medications I was on but for klonopin since there are some triggers I cannot avoid. Food did this. Food and having a good doctor who did not give up on me. Food and knowing what my genetics are. I get that some people might benefit from Yoga, etc, but to serve a blanket statement like that is just ignorant of the genetic and environmental diversity of humanity. I have these genetics because I have Sami heritage and I am adapted to live in a cold climate and eating low purine, high zinc foods. Zinc also helps me break down the purines by stimulating LACC1, which is a sort of PNP backup. A zinc deficiency when I was young left me with an undecended testicle because of my LACC1 genetics. https://www.uniprot.org/uniprotkb/Q8IV20/entry https://www.uniprot.org/uniprotkb/Q8IV20/entry
  - seper8 2y ago
    Super interesting, thanks for sharing
  - jaggederest 2y ago
    Thank you for posting the genetic polymorphism, makes it much easier to cross reference. Glad you've found an answer!
  - dukeofdoom 2y ago
    Thank you, interesting read. My friend that has an autistic son, wants to cure him through diet changes. Do you know anything food related to autism?
    - FollowingTheDao 2y ago
      Not really, but this may be a good start: Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935591/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935591/ and https://www.mdpi.com/2218-1989/10/5/184 https://www.mdpi.com/2218-1989/10/5/184 I do not think the spectrum of autism are caused by a single gene or environmental factor. I was diagnosed with Asperger's as well, much too late in life.