I am pessimistic about purely in silico or even in vitro methodd to tackle a problem as complex as aging rates. Improving mouse models to incorporate a high lev

I am pessimistic about purely in silico or even in vitro methodd to tackle a problem as complex as aging rates. Improving mouse models to incorporate a high level of genetic diversity is a better first step. This is what our group of resesrchers is doing now. Results are promising and results are also highly dependent in genetics and sex. https://pubmed.ncbi.nlm.nih.gov/36173858/ https://pubmed.ncbi.nlm.nih.gov/36173858/ https://pubmed.ncbi.nlm.nih.gov/34666007/ https://pubmed.ncbi.nlm.nih.gov/34666007/ https://pubmed.ncbi.nlm.nih.gov/34552269/ https://pubmed.ncbi.nlm.nih.gov/34552269/